Rob Reiner, the director of When Harry Met Sally and Stand by Me, has been found dead inside his Los Angeles home with his wife Michele Singer.
Investigators believe the filmmaker and actor, 78, and Singer, 68, suffered stab wounds and said a family member is being questioned.
A spokesperson for the Reiner family told CNN: "It is with profound sorrow that we announce the tragic passing of Michele and Rob Reiner. We are heartbroken by this sudden loss, and we ask for privacy during this unbelievably difficult time."
Meanwhile, Los Angeles Police Department deputy chief Alan Hamilton told a press conference that the investigation was being handled by the LAPD's robbery homicide division, stating it would "continue over the coming days".
Reiner, the son of comedy legend Carl, met Singer in 1989 while he was directing romantic comedy When Harry Met Sally, starring Billy Crystal and Meg Ryan.